| 2012年至今已發表的論文 1. Insights into quinaldic acid moiety formation in thiostrepton biosynthesis facilitating fluorinated thiopeptide generation. Lian Duan#; Shoufeng Wang#; Ri Jing Liao; Wen Liu*. Chem.Biol.,2012,19, 443-448（IF: 6.64）. 2. Opportunities and challenges from current investigations into the biosynthetic logic of nosiheptide-represented thiopeptide antibiotics. Shoufeng Wang; Shuai-xiang Zhou; Wen Liu*. Curr. Opin. Chem. Biol.,2013,17, 626-634（IF：9.85）. 3. Discovery and efficient synthesis of a biologically active alkaloid inspired by thiostrepton biosynthesis. Qing-Fei Zheng; Shoufeng Wang*; Wen Liu*. Tetrahedron,2014,70, 7686-7690（IF：2.64）. 4. Target-oriented design and biosynthesis of thiostrepton-derived thiopeptide antibiotics with improved pharmaceutical properties. Shoufeng Wang#；Qingfei Zheng#；Jianfeng Wang； Zhixiong Zhao；Qingye Li；Yunsong Yu; Renxiao Wang; Wen Liu*. Org. Chem. Front.,2015,2, 106–109（IF：4.69）. 5. Thiopeptide antibiotics exhibit a dual mode of action against intracellular pathogens by affecting both host and microbe. Qingfei Zheng#; Qinglan Wang#; Shoufeng Wang#; Jiequn Wu; Qian Gao*; Wen Liu*. Chem. Biol.,2015,22, 1002-1007（IF: 6.64）. 6. Concurrent modifications of the C-terminus and side ring of thiostrepton and their synergistic effects with respect to improving antibacterial activities. Shoufeng Wang#*; Qingfei Zheng#; Jianfeng Wang; Dandan Chen; Yunsong Yu; Wen Liu*. Org. Chem. Front., 2016,3, 496-500（IF：4.69）. 7. Precursor-directed mutational biosynthesis facilitates the functional assignment of two cytochromes P450 in thiostrepton biosynthesis. Qingfei Zheng#; Shoufeng Wang#*; Rijing Liao; Wen Liu*. ACS Chem. Biol.,2016,11, 2673?2678（IF：5.09）. 8. An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization. Qingfei Zheng#, Shoufeng Wang#, Panpan Duan, Rijing Liao, Dandan Chen, Wen Liu*. Proc. Natl. Acad. Sci. USA., 2016,113, 14318-14323（IF：10.28）.
|
